This is my wife and her new S&W J-frame. This is 5 rounds of round nose 180 grain 38 specials.
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Monday, December 26, 2011
Tuesday, December 20, 2011
S&W Model 642CT Centennial revolver: Lightweight Security
I like the autos for many reasons but the revolver still has much to offer the police officer or armed citizen: proven reliability, simplicity, and ease of use. For those unfamiliar with guns and some women, a quality revolver is generally an ideal gun. Here I do a "combat" review of a Smith and Wesson Model "Centennial" 642CT lightweight revolver in .38 Special +P chambering. It's an outstanding choice for concealed carry, backup gun, or in-house security. It's amazingly feathery at only 15.5 oz and as such beats many semi-auto handguns in that department. Other upsides include a full stainless steel barrel (no composite or liner construction here), beautiful matte finished, tough aluminum frame, superb quality throughout, tight lockup, wonderful trigger, excellent grips, and the typically fast S&W cylinder latch. This 642 model also feature very comfortable and very useful Crimson Trace laser grips which add a measure of proven deterrence against bad guys (better to never have to fire a shot I say). Downsides might include very limited firepower at 5 rounds, high cost (0-ish!), bulkier width for concealment, bad sights (they are horrible), need for bulky speed loaders, and inability to fire single action in this Centennial version. In lightweight revolvers, I prefer the shrouded but accessible hammer on the S&W "Bodyguard" 638 Model, just in case you have to make a longer range accurate shot. But this of course is no target gun...intended for self-defense within ...
Thursday, December 15, 2011
Hogue S&W J Frame Round Butt Pau Ferro Premium Wood Grips
!±8± Hogue S&W J Frame Round Butt Pau Ferro Premium Wood Grips
Rate :
| Price : $55.99 | Post Date : Dec 15, 2011 17:08:48Usually ships in 24 hours
Fits: Smith & Wesson J Frame Round Butt. Models 30, 32, 34, 36, 37, 38, 39, 51, 60, 317, 340, 351PD, 360PD, 431PD, 432PD, 442, 637, 638, 640, 642, 649, 650, 651, 940, Centennial, Chief Special, etc. Hogue fancy hardwood grips are in a class of their own, and are acclaimed by many as the finest handgun stocks available. All Hogue hardwood grips are precision inlet on modern computerized machinery (CNC), then hand finished on actual factory frames, assuring a proper fit. Finally, they are hand polished to a non-slippery sheen using natural Carnauba wax which will not crack and peel like cheap, sprayed-on finishes. Hogue wood grips are made from Pau Ferro wood. Looks like dark walnut.
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Saturday, December 10, 2011
Monday, December 5, 2011
Crimson Trace Lasergrip for Smith and Wesson J-Frame Defender Series Round Butt, Black
!±8±Crimson Trace Lasergrip for Smith and Wesson J-Frame Defender Series Round Butt, Black
Brand : Crimson TraceRate :
Price : $179.00
Post Date : Dec 05, 2011 13:34:08
Usually ships in 24 hours
If you ever need to defend yourself with your revolver, chances are it won’t be from a perfect shooting position. And it will all happen lightning fast. But on your side, you’ll have lasergrips’ dependable speed and accuracy. Whether it’s the amazingly quick targeting, or just the overall instinctive simplicity of use Crimson Trace helps you survive.
Friday, December 2, 2011
".357 magnum blaster in stainless"
Smith and Wesson model 66 .357 stainless revolver. A truly awesome pistol easy to shoot clean and reliable
Sunday, November 27, 2011
S&W 686P: "Full Power Option" by Nutnfancy
How could a 7-shot 39.5 oz revolver be a favorite of Nutnfancy?! Two words: Shooting it! To shoot the Smith and Wesson 686 (or in this case the 686 Plus or P) is to love it. Yes it still is a limited capacity revolver that's heavy and a bit bulky. But in certain POUs, as discussed, the weight of this stainless steel 686P is ideal and appropriate. This 4 inch barreled 686P is steady on target with a perfect balance that inspires confidence. My selected POU on this full-sized .357 Magnum combat revolver is primarily (but not limited to!) range use and as a recreational target gun. For me it is a joy to shoot. One reason for this: the amazingly smooth and light double and single action trigger as factory-modified by the Smith and Wesson Performance Center. That makes it fast to shoot and the double action is my preferred firing methodology with this 686P. Add in the typical but still excellent high contrast SW sights, a smooth and wide trigger face, full lugged barrel (great balance), fast and sure ejection of empties (usually), grip cutouts for speed loader use, good Hogue rubber grips, intuitive cylinder release, and excellent accuracy and you can understand my enthusiasm. Also in the review I roll in a pristine 4 inch Colt Python .357 for some interesting comparisons as I cover some their details side by side (two gun reviews in one!). Both are outstanding in most roles but the 686P wins more ergonomic points with me; the Colt Python on wins on absolute cool and ...
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Friday, November 25, 2011
Current Status of Enzyme Therapy in the Management of Chronic Disorders
Enzymes:
Enzymes are present in organisms as single units or in multienzyme complexes. Posttranslational modifications of amino acid residues take place after peptide assembly on the ribosome; hydroxylation, phosphorylation, sulfation, N-terminal acetylation, and glycosylation are a few examples. The nature of posttranslational modifications and the hydrophobicity of amino acid side chains determine whether the enzyme is free or membrane-bound.1, 2
Enzymes catalyze biochemical reactions in living systems which would otherwise proceed too slowly at physiological temperature and pH to sustain life. Specificity and high catalytic power are two special attributes of enzymes which distinguish them from ordinary chemical catalysts.3
Clinical and pharmaceutical importance of enzymes
A variety of diseases can be detected through altered body fluid levels of specific enzymes.
Table 1 Disease detection via enzymes
Enzyme Disease
Aspartate aminotransferase Liver disease
Alanine aminotransferase Liver disease
Acid phosphatase Prostate carcinoma
Alkaline phosphatase Bone disease, Hepatobiliary disease
Creatine kinase Myocardial infarction, Muscle disease
Lactate dehydrogenase Myocardial infarction, Liver disease
Cholinesterase Organophosphate poisoning
Pancreas enzymes Pancreatic diseases.
glutamyltranspeptidase Liver disease, Alcoholism
Elevated plasma and urine lysozyme levels are typical for lymphocytic leukemia's and degenerative kidney diseases with glomerular and proximal tubular damage. Normalization of lysozyme plasma levels and disappearance of lysozyme in the urine are of prognostic value in successful kidney transplants.
Various types of cancer are associated with a general increase in plasma proteinases. The presence of various plasminogen activators and their inhibitors in many malignancies suggests that the fibrinolytic system is involved in the regulation of tumor growth and metastatis. Local changes in fibrinolytic activity such as reduced tPA and increased urokinase levels in biopsies of the intestinal mucosa are characteristic in inflammatory and (pre)malignant processes in the colon.4
Replacement therapy in enzyme dysfunction or as adjusting agents in biochemical processes that have gone awry. Examples include, Fibrinolytic enzymes in thrombotic disorders; Proteolytic enzymes in wound healing; Amino acid degrading enzymes and Dimeric ribonuclease in cancer therapy; Digestive enzymes; Hyaluronidase and superoxide dismutase in inflammations, and many others.
Enzymes of nonhuman origin sometimes are potent immunogens or allergens. Their delivery systems must protect them from inactivation before the target side is reached, and yet allow the enzymes to be released at the target site, eventually with their specific cofactors if required. Nonetheless enzymes are attractive drugs because of their specificity and efficiency.5
Enzyme inhibitors:
Natural and synthetic enzyme inhibitors have become increasingly important in medicine, and have developed into a separate class of drugs. These inhibitors form tight noncovalent or irreversible covalent complexes with their target enzymes.6,7
Thrombin is a key enzyme in clot formation, acting as a catalyst of conversion of fibrinogen to fibrin. Hirudin, a potent thrombin inhibitor from leech extracts, is available as a recombinant polypeptide and is currently under investigation in various clinical trials.8,9
The bovine basic pancreatic proteinase inhibitor aprotinin inactivates kallikrein and is used successfully in supplementary treatment of acute pancreatitis and shock.10Rennin inhibitors such as pepstain are currently under investigation to lower blood pressure.11,12
Enzyme in therapy:
Genetic defects 13, 14
Metabolic diseases are caused by specific enzyme defects, in which the enzyme is not expressed or is dysfunctional due to a sequence mutation or posttranslational inactivation. Some of these diseases can be treated with controlled diets. For example, phenylketonuria caused by phenylalanine-hydroxylase deficiency requires a phenylalanine-free diet. More often replacement therapy is needed, requiring the targeting of a replacement enzyme toward specific organs or tissues.
Other well-known" inborn errors of metabolism" are Pompe's disease or type II glycogen-storage disease in which deficient ±-1,4-glucosidase results in excessive accumulation of glycogen in liver and muscle cell lysosomes, Alcaptonuria (deficienct homogentisate 1,2-dioxygenase), Hemophilia B (factor IXa), Galactosemia( UDPG-hexose-1-phosphate transferase), Gaucher's disease (²-glucocerebrosidase), Von Gierke's disease (glucose-6-phosphatase), Pentosuria (xylulose reductase), Nieman-Pick disease (Sphingomyelin phosphodiesterase), and the Lesch-Nyhan syndrome in which the absence of hypoxanthine-guanine phosphoribose transferase causes impaired nucleotide metabolism in brain cells and results in a severe neurological disorder.
Cancer therapy:
L-Asparaginase is used as an anticancer drug. Certain tumor cell types lack asparagines synthetase activity and need this amino acid as an essential nutrient, in contrast to normal cells. Asparaginase selectively kills the tumor cells by depleting the circulating level of asparagines. It has also been suggested that L-aspartate as a metabolite may be toxic toward neoplastic cells. 15
Acute lymphocytic leukemia treatment with asparaginase is relatively successful; some studies report complete remission in up to 60% of the treated patients.16 Patients subject to prolonged treatment with the enzyme often develop a resistence due to the high titer of their neutralizing antibodies. Nevertheless, the therapeutic index of asparaginase compares very favorably to other antileukemic drugs.
It was speculated that certain types of cancer cells might also lack other particular pathways for amino acid synthesis and thus have amino acid requirements that are masked because of the presence of these amino acids in the diet. Enzyme therapy depleting the required amino acid would lead to the selective killing of these cells. Glutamine, Cysteine, and Arginine have been the subject of studies for possible enzyme-depletion therapy. In addition to the E.coli and Erwinia asparaginase, two types of glutaminase-asparaginase (PGA and AGA) might be suitable therapeutic enzymes since both have antitumor activity in experimental animal models.17 Allergic reactions and some times neurotoxicity were the most serious side effects. The use of polymerized enzyme is preferred, since the unmodified enzyme has a plasma half-life of only 80 min.18
Of particular interest in cancer therapy is Carboxypeptidase G which hydrolyzes the terminal aspartate and glutamate moieties in oligopeptides and the glutamate moiety in reduced and nonreduced folates. Purified carboxypeptidase G from various Pseudomonas strains prevents methotrexate toxicity in humans.19
The antineoplastic effect of bovine pancreas ribonuclease has been reported in chronic myelocytic leukemia patients. However, limited information is available from clinical trials. Dimeric ribonuclease displays selective toxicity in animal tumors and may be a promising candidate as therapeutic enzyme.
Bacteriolytic, antiviral, and anti-inflammatory enzymes:
Lysozyme is present as an antibacterial agent in body fluids and cavities in direct contact with the external environment. It is available as a pharmaceutical preparation in tablets, ointments, powders, and infusions and is used as an antibacterial, antiviral, and anti-inflammatory drug. The commercial preparations contain hen egg-white lysozyme which is easily isolated and purified from egg whites in large-scale projects. This enzyme is nontoxic and only weakly antigenic and can be administered internally in large doses without significant side effects. Lysozyme has chitinase, muramidase, and transglycosidase activity and acts upon bacteria in many ways. The proteoglycan layer in cell walls is the natural substrate for this enzyme.
Lysozyme has a distinct antiviral activity against herpes labialis, zoster, and simplex I and II types in humans, as well as against some oncogenic viruses in animal studies. Lysozyme stimulates phagocytosis and favors wound healing and regression of degenerative and necrotic processes.20 Lysozyme is administered in intramuscular or parenteral injections in herpes zoster and viral hepatitis, and in ointments for the treatment of herpetic keratitis, burns, and wounds and gynecological infections.
Corticoids and antibiotics have a synergestic action and are combined with lysozyme in aerosols for the treatment of bronchopulmonary diseases. Proteolytic enzymes and antiseptics are frequently used as adjuvant agents for dermatological applications. Bovine pancreatic ribonuclease appears to be an effective antiviral enzyme against tick-borne encephalitis. It has no side effects and results in more rapid temperature normalization and regression of meningeal symptoms than antiencephalitic gamma globulin.21
Commercial hyaluronidase preparations contain the bovine-testicular type (hyaluronate-4-glycanohydrolase) or the leech-type enzyme (hyaluronate-3-glycanohydrolase). They are used in the treatment of keloids, ligneous conjunctivitis, and connective-tissue inflammation and as adjuvant in cancer therapy to facilitate transport and resorption of cytostatic agents.22 Animal studies revealed that hyaluronidase also acts as a cardiac lymphagogue, thereby reducing myocardial infarction after coronary artery occlusion.23
Superoxide dismutase (SOD) acts as an oxygen radical scavenger; under inflammatory conditions its levels are increased. Depending on the nature of the disease, SOD is administered in injections, encapsulated in liposomes as a copper-zinc-SOD complex, or externally in creams.24 the enzyme is effective in the treatment of rheumatoid arthritis, crohn's disease, progressive systemic sclerosis, dermatitis herpetiformis, and mucocutaneous lymph-node syndrome. It also prevents myocardial injury as a consequence of chemotherapy in neoplstic diseases.25
Proteolytic enzymes:
Enzymes hydrolyzing peptide bonds are not only important in food digestion, but also play essential roles in biological processes such as coagulation and hemostasis, complement activation, peptide hormone release, wound healing, and control of protein metabolism.25,26
Trypsin and chymotrypsin are classical examples of proteinases used in wound healing. They facilitate the removal of necrotic tissue and scab material trapping bacteria inside the wound. These enzymes are frequently combined with antiseptics or antibiotics in ointments and bandages. Recently a new enzyme extract from Antarctic krill (E.superba) has been tested as a possible candidate preparation for the debridement of ulcerative lesions.28
Antithrombotic therapy:
An imbalance between coagulation and fibrinolysis leading to excessive fibrin deposition can be approached either by the reduction of the coagulation potency or by an increase of the fibrinolytic potency. Various aspects of fibrinolytic enhancement are still under development. Thrombolytic thearpy is used in the initial management of patients with deep venous thrombosis and pulmonary embolism.
Streptokinase and urokinase have been used extensively in the treatment of venous thromboembolism. They are more potent than free circulating plasmin, which is rapidly inactivated by circulating alpha 2-antiplasmin 30, 29. Randomized studies have demonstrated that intravenous tissue plasminogen activator is more efficient than streptokinase in the treatment of coronary occlusion in acute myocardial infarction 31, 32. Commercial recombinant tissue plasminogen activator for the treatment of acute myocardial infarct is mainly obtained from Chinese hamster ovary cells (CHO).
Chemonucleolysis:
Chymopapain, an oxidation-sensitive cysteine proteinase from Carica papaya has been proposed for the treatment of herniated lumbar discs. Intradiscal injection of chymopapin results in dissolution of the mucopolysaccharide - protein complex of an extruding nucleus pulposus, the centre cushioning of gelatinous mass lying within the intervertebral disc, thereby relieving the pain associated with a pressurized nerve. Large-scale follow-up studies indicate that chemonucleolysis is as successful a procedure as surgical discectomy, with a 76-80% success rate in both groups 33, 34, 35. Some pathological peculiarities associated with herniated discs might be unfit for treatment by chemonucleolysis, for example, discs extruding nucleus pulposus through the annulus, a case in which the risk of damage to the spinal cord is predominant .36
Pancreas enzymes:
Digestion of food is facilitated by the pancrease enzyme trypsin, chymotrypsin and elastase, carboxypeptidase A and B, phospholipase A - 2 and lipase and amylase. The main lipid component in food is long-chain triacylglycerol, which is hydrolyzed into fatty acids and sn-2-monoacylglycerol. Both products are readily absorbed in the intestine. This hydrolysis is catalyzed sequentially by gastric lipase secreted by the chief cells of the stomach and by colipase-dependent pancrease 37.
Pancreatic lipases, proteases and amylases are prescribed as replacement therapy in pancreatic insufficiency where the enzyme output has fallen below 10%. Pancreatin of mammal origin is used in commercial preparations for substitution treatment 38, 40. Pharmaceutical formulations show considerable variation in enzyme activity and bile salt content. Cellulose is sometimes added as adjuvant enzyme. Since the extent of pancreas malfunction varies significantly among patients, individualization of the treatment is indicated in determining the optimal enzyme dosage, formulation type, time of administration with respect to meals and frequency of administration.
Conclusion and future trends:
The elucidation on a molecular level of disease-related biochemical processes enables the definition of the type and specific target area of key enzymes or inhibitors necessary for restoring normal physiological conditions. Enzymes are attractive drug candidates because of their reaction specificity and catalytic efficiency. However, their protein nature imposes some limitations on their use in therapy. Organ specific targeted enzymes require parenteral administration and proteins of non-human origin are often allergenic or immunogenic. Considerable progress has been made in the refinement of isolation procedures to reduce or eliminate toxic contaminants, and the development of specific chemical modification and targeting techniques offers new possibilities for prolonging half life and improving enzyme bioavailability. The most promising results are undoubtedly to be expected from the field of genetic engineering and site specific mutagenesis. Mutant enzymes with altered or improved specificity, enhanced stability, and reduced immunogenicity will become available at an affordable cost.
References:
1. Chou, P. Y., and Fasman, G. D., Biochemistry, 13:222 (1974).
2. Moss, D. W., Henderson, A. R., and Kachmar., J. F., Enzymes. In: Textbook of Clinical chemistry (N. W. Tietz, ed.), W. B. Saunders, Philadelphia, 1986, pp. 619-774.
3. Ruyssen, R., and Lauwers, A. R., eds. Pharmaceutical enzymes, E. Story-Scientia, Ghent, Belgium, 1978.
4. Bickerstaff, G. F., and New Studies in Biology: enzymes in industry and medicine, Edward Arnold publish ltd., London, Baltimore, 1987.
5. Holcenberg, J. S., and Roberts, J., Enzymes as drugs, Wiley, New York, 1981.
6. Horl, H., and Heildland, A., eds., proteases: potential role in health and disease, In: advances in experimental medicine and biology, vol. 167, plenum press, new York and London. 1982.
7. Olson, S. T., and Shore, J. D., J. Biol. Chem., 257:14895-14895 (1982).
8. Kuada, T., and Abiko, Y., Thromb. Res., 24:285-298 (1981).
9. Witting J. I., Pouliott, C., Catalfamo, J. L., Fareed, J., and Fenton, II, J.F., Thromh res., 50:461-468 (1988).
10. Reimerdes, E. H., and Klostermeyer, H., Methods Enzymol., 15:26-28 (1976)
11. Illiano, L., Demeester, J., and Lauwers, A., Arch. Int. Phsiol. Biochem. 90(1):B36-37 (1982).
12. Schnebli, H. P., and Braun, N. J., Proteinase inhibitors as drugs, In: Research monographs in cell and tissue physiology, vol. 12, Proteinase inhibitors (A. J. Barrett and G. Salvesen, ed.,), Elsevier, New York, Amsterdam, 1986, pp. 613-627.
13. Powers, J. C., Am. Rev. Resp. Dis., 127 (supplP: S54 (1983).
14. Asgar, S. S., Pharmacol., Rev., 36:223-244(1984).
15. Kidd, J. G., Exp. Med., 98:565-581, (1953).
16. Capizzi, R. L., and Cheng, Y. C., therapy of neoplasia with asparaginase. In: Enzymes as drugs (J. S. Holcenberg and J. Roberts, eds.,) Wiley, New York, 1981, pp. 1-24.
17. Roberts, J., Schmid, F. A., and Rosenfeld, H. J., Cancer Treat Rep. 63:1045-54 (1979)
18. Spiers, A. S. D., and Wase, H. E., Cancer Treat Rep. 63:1019-24 (1979)
19. Abelson, H. T., Ensminger, W., Ropsowki, A., and Uren, J., Cancer Treat Rep. 62:1549-52 (1978)
20. Canfield, R. E., Collins, J.C., and Sobel, J. H., Lysozyme, 1st ed., Academic Press, New York, 1974
21. Levy, C. C., and Karpetsky, T. P., Human Ribonucleases. In: Enzymes as drugs (J. S. Holcenberg and J. Roberts, eds.,) Wiley, New York, 1981, pp. 156.
22. Baumgartner, G., and Neumann, H., Laryngol, Rhinol, Otol. Stuttg., 66:195 (1987)
23. Szlavy, L., Koster, K., De Courten, A., and Hollenberg, N. K., Angiolgy, 38:73- 84 (1987)
24. Bulkley, G. B., Br. J. Cancer Suppl., 8:66-73 (1987)
25. Niwa, Y., somiya, K., Michelson, A. M., and Puget, K., Free Radic. Res. Commun., 1:137-153(1985)
26. Reich, E., Rifkin, D. B., and Shaw, E., ed., Proteases and Biological control, cold spring harbor laboratory, cold spring harbor, New York, 1975
27. Ribbons, D. W., and Brew, K., eds. Proteolysis and Physiological Regulations, Academic Press, New York, 1976
28. Anheller, J. E., Hellgren, L., Karlstam, B., and Vincent. J., Arch., Dermotal., Res., 281:105-110 (1989)
29. Smith, R. A. G., Dupe, R. J., English, P. D., and green, J., nature, 290:505-508 (1981)
30. Ranby, M., and Wallen, P., In: Thrombolysis: biological and therapeutic properties of new thrombolytic agents ( D. Collem and H. R. Lijnen ed.,), Churchill livingstone, Edinburgh, 1985, pp. 31-48
31. Verstraete, M., Bernart, R., Bory. M., et al., Lancet, 1985:842-847
32. Trials in Myocardial infarction, phase I findings, N. Engl. J. Med., 312:932-936 (1985)
33. Hill, G. M., and Ellis, E, A., Clin. Orthop., 225:229-233 (1987)
34. Bock-Lamberlin, P.R., rose, F. W., and Schwonbeck, M., Zeitschr, Ortchop., 126:661-665 (1988)
35. Alexander, A. H., burkus, J. K., Mitchell, J. B., and ayers, W. V., Clin. Orthop., 244:158-165 (1989)
36. DATTA panel, JAMA. 262:956 (1989)
37. Szypryt, E. P., Gibson, M. J., Mulholland, R. C., and Worthington, B. S., Spine, 12:707-711 (1987)
38. Takenake, Y., Revel, M., Kahan, A., and Amor, B., Spine, 12:556-560 (1987)
39. Moreau, H., Gargouri, Y., Bernadal, A., Peironi, G., and Verger, R., Rev. Fr. Corps Gras, 35:169-176 (1988)
40. Peschke, G. J., Pancreatic enzyme (pancreatin). In : Topic in pharmaceutical sciences, 1989 (D. D. Breimer, D. J. A. Crommelin, and K. K. Midha eds., ), SDU publishers, the hague, Netherlands, 1989, pp. 129-142.
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Wednesday, November 23, 2011
Lasergrip Rubber Wrap-Around S&W J Frame Round Butt Revolver
!±8±Lasergrip Rubber Wrap-Around S&W J Frame Round Butt Revolver
Brand : Crimson TraceRate :
Price : $300.99
Post Date : Nov 23, 2011 23:31:15
Usually ships in 1-2 business days
Description:
Revolver Lasergrips
Additional Information:
Smith & Wesson J Frame Round Butt
Rubber overmold grip. Front activation pressure switch. Master on/off switch. Two #2032 Lithium batteries. Over four hours of illumination. Precise windage and elevation adjustments. Single screw attachment. Fits Airlight, Airweight, Bodyguard, Chief's Special, Centennial, Ladysmith, Models 36, 37, 38, 49, 60, 63, 317, 331, 332, 337, 340, 342, 351, 360, 442, 637, 638, 640, 642, 649, 651 and 940.
Monday, November 21, 2011
Speed Paddle Holster For Charter Arms Undercover/Smith & Wesson
!±8± Speed Paddle Holster For Charter Arms Undercover/Smith & Wesson
Brand : Galco | Rate : | Price : $70.99
Post Date : Nov 21, 2011 04:17:36 | Usually ships in 1-2 business days
| Price : $70.99Post Date : Nov 21, 2011 04:17:36 | Usually ships in 1-2 business days
Description:
Speed Paddle
Designed exclusively for revolvers. Constructed of premium saddle leather and features an open top design, covered trigger guard and tension screw adjustment. Includes Galco's patented copolymer injection-molded belt lock paddle, which makes it possible to put on and take off this holster without removing your belt.
Additional Information:
Charter Arms; Smith & Wesson; Taurus
Charter Arms Undercover 2 inch; Smith & Wesson J frame 36, 2 inch, 442, 60 2.125 inch .357/.38, 649 Bodyguard 2 inch, 640 Centennial 2.125 inch .357/.38; Taurus 85 2 inch, 85CH 2 inch
Wednesday, November 16, 2011
What is the Difference Between Mace and Pepper Spray?
If you are considering pepper spray as your self defense weapon of choice, you may be wondering about the difference between MACE and pepper spray.
Actually, they are one and the same. MACE is just a brand name of pepper spray. In the same way that the actual brand name Kleenex is used to represent facial tissue, the brand 'MACE' has come to represent the pepper spray industry. Originally called "Chemical Mace," and manufactured by a division of Smith & Wesson since the 1960s. Today, it is a brand of Mace Security International.
Although early formulas were actually tear gas, and therefore there was a difference between Mace and pepper spray, today formulas are pepper sprays, similar to those made by other companies. Although traditional Mace (the tear gas formulation) is still in existence, it has been banned in most Western countries.
The original formula is a very different substance from today's pepper-spray, which uses Oleoresin Capsicum (OC), the same active ingredient that is found in many modern pepper sprays. The percentage of OC in the formula you purchase, which generally varies from 1% to 10%, has very little to do with how effective the product is.
Buying a product with higher concentrations of OC does not necessarily mean that it is a more effective self defense product than pepper sprays with lower OC concentrations. These personal security products are very effective, non-lethal weapons used by the military, law enforcement officers, and the public.
Pepper Spray immediately goes to work dilating capillaries when sprayed into the eyes, nose and throat and the effects will last anywhere from 15-60 minutes and can result in temporary blindness, shortness of breath and coughing!
Choosing a specific canister as a self defense weapon can be a very confusing choice, especially with so many brands and chemical formulas on the market today, not to mention different canister types. Mace is one of the most highly regarded pepper spray manufacturers today; Fox Labs is another well-known brand.
While there are some differences between the brands, mainly in the SHU ratings, for the most part pepper spray is widely comparable between brands. Mace sprays may also include additional features over regular pepper spray, such as tear gas ingredients for added effect, or the use of gel or foam carriers rather than liquid carriers like regular pepper spray. This gives the canister a longer firing range so that you can remain a longer distance away from your attacker.
Like other formulations, Mace pepper spray is available in many different-sized canisters. It can also be found in the form of a Mace personal alarm or even a Mace pepper spray gun for accurate delivery.
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Sunday, November 13, 2011
Galco Ankle Lite / Ankle Holster for S&W J FR 60 2 1/8 .357 .38 (Black, Left-hand)
!±8±Galco Ankle Lite / Ankle Holster for S&W J FR 60 2 1/8 .357 .38 (Black, Left-hand)
Brand : GalcoRate :
Price : $57.56
Post Date : Nov 13, 2011 17:21:27
Usually ships in 24 hours
After two decades of universal praise for the Ankle Glove, Galco has added the Ankle Lite to the Concealed Carry Lite family of holsters. Using the same wide neoprene ankle band and Velcro closure as the Ankle Glove with Center Cut Steerhide for the holster, the Ankle Lite combines extended wearing comfort with unmatched security. Additional comfort is provided by sheepskin padding between the holster and ankle, while speed of draw is enhanced with a reinforced thumb break retention strap. The Ankle Lite may be worn with or without the optional adjustable calf strap (sold separately), and accommodates ankles up to 13" in circumference. Made for semiautomatic pistols and double-action revolvers, the Ankle Lite is available in right or left hand draw in black or khaki finish.
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